• Antimicrobial susceptibility profiles of clinically important bacterial pathogens at the Kamuzu Central Hospital in Lilongwe, Malawi 

      Choonara, Faheema E.; Haldorsen, Bjørg; Ndhlovu, Isaac; Saulosi, Osborne; Maida, Tarsizio; Lampiao, Fanuel; Simonsen, Gunnar Skov; Essack, Sabiha Y.; Sundsfjord, Arnfinn (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-01)
      Background The aim of this prospective study was to ascertain antimicrobial resistance (AMR) in clinical bacterial pathogens from in-hospital adult patients at a tertiary hospital in Lilongwe, Malawi. Methods<p> <p>Clinical specimens (blood culture, pus, urine and cerebrospinal fluid) collected during June to December 2017 were examined for bacterial growth in standard aerobic conditions. One ...
    • Molecular Epidemiological Characterisation of ESBL- and Plasmid-Mediated AmpC-Producing Escherichia coli and Klebsiella pneumoniae at Kamuzu Central Hospital, Lilongwe, Malawi 

      Choonara, Faheema Ebrahim; Haldorsen, Bjørg; Janice, Jessin; Mbanga, Joshua; Ndhlovu, Isaac; Saulosi, Osborne; Maida, Tarsizio; Lampiao, Fanuel; Simonsen, Gunnar Skov; Essack, Sabiha Yusuf; Sundsfjord, Arnfinn (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-14)
      The global rise in infections caused by multidrug resistant (MDR) Enterobacterales poses a public health problem. We have performed a molecular epidemiological characterisation of representative plasmid-mediated AmpC (pAmpC) and ESBL-positive clinical isolates of Escherichia coli (n = 38) and Klebsiella pneumoniae (n = 17) from a tertiary hospital in Malawi collected in 2017. BlaCTX-M-15 was the ...